Abstract Dr. Draganjac
Chromium Complexes with Hexadentate Bipyridyl Ligands
By using laser flash photoylsis, understanding of mechanistic issues within the cell has improved. A photochemically active reactant is attached to the protein to be studied, photolyzed, and potentially electron transfer occurs from the reactant to the protein. This "activated" protein is complexed with a second protein. The activated protein then transfers an electron to the complexed protein. This reaction is studied spectrophotometrically and gives information on reaction rates between metalloproteins. Typically Ru complexes of bipyridine have been used as the photochemically active reagent. This study will look at Cr complexes of a hexadentate bipyridine ligand as the photochemically active reactant. The hexadentate ligand 1,3,5-tris((5'-methyl-2,2'-bipyridin-5-yl)ethyl)benzene will be used to prevent metal labilization in solution. The advantage to using Cr(III) is longer lifetimes in the excited state. If successful, complexes of Mo and W will be investigated.
Updated 10/31/2005
The Arkansas INBRE is Supported by a grant from the
National Institutes of Health
and the
National Center
for Research Resources (P20 RR-16460).
Please contact Caroline Miller Robinson regarding questions or comments about this site or our program. For more information about the University of Arkansas for Medical Sciences visit http://www.uams.edu.
