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Denton abstract

Abstract Dr. J Denton

Denton Web Site

 

Title Adipocyte-macrophage interactions in obesity

Synopsis:

Visceral obesity is a major risk factor for the development of type 2 diabetes, hypertension and cardiovascular disease. An emerging paradigm is that macrophage infiltration into visceral fat establishes a vicious cycle of pro-inflammatory signaling that contributes to the development of the metabolic syndrome. I will discuss very recent work from our laboratory aimed at defining the molecular mechanisms and signaling pathways that trigger adipose tissue inflammation in obesity.


 

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Updated 08/29/2006

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and the National Center for Research Resources (P20 RR-16460).

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